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- <text id=93TT1355>
- <title>
- Apr. 05, 1993: Deadly Copies
- </title>
- <history>
- TIME--The Weekly Newsmagazine--1993
- Apr. 05, 1993 The Generation That Forgot God
- </history>
- <article>
- <source>Time Magazine</source>
- <hdr>
- THE WEEK, Page 19
- HEALTH & SCIENCE
- Deadly Copies
- </hdr>
- <body>
- <p>Researchers locate the gene that causes Huntington's disease
- </p>
- <p> Finding certain genes can be as difficult as locating a phone
- number without an address or a last name. Ten years after
- researchers figured out that the gene that causes Huntington's
- disease, an uncommon degenerative brain disorder, was located
- somewhere on the fourth of 23 pairs of human chromosomes, an
- international team of scientists has pinpointed the actual
- hereditary entry responsible for the disease.
- </p>
- <p> What they found was a biochemical equivalent of a
- debilitating stutter: a defective gene that includes too many
- copies of one crucial subsection of the DNA molecule. The more
- extra copies, the more severe the symptoms and the sooner they
- occur. In the past two years, three other conditions, including
- a form of muscular dystrophy, have been traced to such
- hereditary hiccups. With the Huntington's gene in hand,
- researchers can now develop more accurate diagnostic tests. They
- may also prove better able to predict at what age a person will
- succumb to the disease.
- </p>
-
- </body>
- </article>
- </text>
-
-